Medicine Information

iventi-d

Name: iventi-d
Brand: iventi-d
Rating: 4.5 (117 reviews)

Eye DropMoxifloxacin 0.5% and Dexamethasone 0.1%Ophthalmic Preparations, Anti-infectives with CorticosteroidsATC: S01CA01

Generic Name

Moxifloxacin 0.5% & Dexamethasone 0.1% Eye Drop

Manufacturer

Square Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
iventi d 05 01 eye drop	৳ 240.00	N/A

Description

Overview of the medicine

iventi-d eye drop is a combination medicine containing Moxifloxacin (a fluoroquinolone antibiotic) and Dexamethasone (a corticosteroid). It is used to treat bacterial eye infections and inflammation.

Uses & Indications

Bacterial conjunctivitis

Bacterial keratitis

Blepharitis with bacterial infection

Post-operative inflammation where bacterial infection is suspected or prophylaxis is needed

Dosage

Adults

1 drop in the affected eye(s) 2-4 times daily, or as directed by a physician. Treatment duration is typically 5-7 days.

Elderly

No specific dosage adjustment required; use as per adult dosage, or as advised by a physician.

Renal_impairment

No dosage adjustment required for renal impairment, as systemic absorption is minimal.

How to Take

For topical ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill one drop into the pouch. Do not touch the dropper tip to the eye or any other surface. Wash hands before and after use. Remove contact lenses before application and reinsert 15 minutes after.

Mechanism of Action

Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Dexamethasone is a potent corticosteroid that suppresses the inflammatory response and inhibits the migration of leukocytes, reducing inflammation, swelling, and redness.

Pharmacokinetics

Onset

Rapid (symptomatic relief may begin within minutes to hours).

Excretion

Systemic excretion (renal/fecal) occurs if significant absorption takes place.

Half life

Local duration of action, systemic half-life is not clinically significant for topical application.

Absorption

Minimal systemic absorption after topical ophthalmic administration; good ocular penetration.

Metabolism

Minimal local metabolism; systemic metabolism (hepatic) occurs if absorbed.

Side Effects

Contraindications

Hypersensitivity to Moxifloxacin, Dexamethasone, or any components of the formulation
Viral diseases of the cornea and conjunctiva (e.g., Herpes Simplex Keratitis, Vaccinia, Varicella)
Mycobacterial infections of the eye
Fungal diseases of ocular structures

Drug Interactions

Storage

Store in a cool, dry place, below 25°C. Protect from light. Keep out of reach of children.

Overdose

Overdose is unlikely with topical ophthalmic administration. If excessive amounts are applied, the eye may be rinsed with lukewarm water. Systemic toxicity from ocular overdose is not anticipated.

Pregnancy & Lactation

Use during pregnancy and lactation only if clearly needed and the potential benefits outweigh the potential risks. Consult a doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 ml bottle

Shelf Life

Unopened: 24 months from manufacturing date. After opening: Discard after 28 days.

Availability

Pharmacies, Hospitals

Approval Status

Approved by relevant authorities (e.g., DGDA)

Patent Status

Off-patent (generic formulation)

Clinical Trials

Extensive clinical trials support the efficacy and safety of Moxifloxacin and Dexamethasone combinations for ophthalmic indications.

Lab Monitoring

Regular monitoring of intraocular pressure (IOP) is advisable for patients on prolonged corticosteroid therapy (typically >10 days).

Doctor Notes

Emphasize monitoring intraocular pressure (IOP) in patients receiving prolonged steroid therapy.
Advise patients on proper administration technique and contact lens management.
Limit treatment duration to minimize steroid-related adverse effects.

Patient Guidelines

Read the patient information leaflet carefully before use.
Do not touch the dropper tip to any surface, including your eye, to avoid contamination.
Do not wear contact lenses during treatment for eye infections, unless advised by your doctor.
Do not use for longer than prescribed by your doctor, as prolonged use may lead to adverse effects.

Missed Dose Advice

If a dose is missed, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Driving Precautions

This eye drop may cause temporary blurred vision or other visual disturbances immediately after administration. If this occurs, do not drive or operate machinery until your vision is clear.