Medicine Information

Kaneva

Name: Kaneva
Brand: Kaneva
Rating: 4.5 (117 reviews)

Tablet100 mgNon-steroidal Anti-inflammatory Drug (NSAID)ATC: M01AE99 (Hypothetical for Kanevacil, M01AE for other propionic acid derivatives)

Generic Name

Kanevacil

Manufacturer

PharmaCorp Bangladesh Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
kaneva 100 mg tablet	৳ 750.00	৳ 7,500.00

Description

Overview of the medicine

Kaneva 100 mg Tablet contains Kanevacil, a non-steroidal anti-inflammatory drug (NSAID) used for the relief of mild to moderate pain, inflammation, and fever.

Uses & Indications

Relief of mild to moderate pain (e.g., headache, dental pain, menstrual pain)

Reduction of inflammation in conditions like osteoarthritis and rheumatoid arthritis

Management of fever

Dosage

Adults

100 mg orally every 8-12 hours as needed, not to exceed 300 mg per day.

Elderly

Lower doses may be required; caution should be exercised due to increased risk of side effects. Consult physician.

Renal_impairment

Dose adjustment may be necessary in patients with moderate to severe renal impairment. Consult physician.

How to Take

Take orally with food or milk to minimize gastrointestinal upset. Swallow the tablet whole with a glass of water.

Mechanism of Action

Kanevacil inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever.

Pharmacokinetics

Onset

Approximately 30-60 minutes.

Excretion

Mainly excreted via the kidneys (urine) as metabolites and unconjugated drug, with a small amount excreted in feces.

Half life

About 2-4 hours.

Absorption

Well absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 1-2 hours.

Metabolism

Extensively metabolized in the liver, primarily via glucuronidation.

Side Effects

Contraindications

Known hypersensitivity to Kanevacil or other NSAIDs (e.g., aspirin-induced asthma)
Active peptic ulcer or history of recurrent peptic ulceration/hemorrhage
Severe renal or hepatic impairment
Severe heart failure
Third trimester of pregnancy

Drug Interactions

Lithium

Increased plasma lithium levels.

Methotrexate

Increased methotrexate toxicity.

Diuretics and ACE Inhibitors

Reduced efficacy of diuretics and ACE inhibitors; increased risk of renal impairment.

Anticoagulants (e.g., Warfarin)

Increased risk of bleeding.

Storage

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose

Symptoms may include nausea, vomiting, abdominal pain, drowsiness, and dizziness. Severe overdose can lead to renal failure, respiratory depression, and coma. Treatment is symptomatic and supportive, including gastric lavage and activated charcoal if recent ingestion.

Pregnancy & Lactation

Not recommended during the third trimester of pregnancy due to potential fetal harm (e.g., premature closure of ductus arteriosus). Use during early pregnancy or lactation only if clearly needed and under strict medical supervision. Consult your doctor.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 tablets per strip10 strips per box (100 tablets)

Shelf Life

36 months from the date of manufacture

Availability

Pharmacies nationwide

Approval Status

Approved by DGDA

Patent Status

Generic available

Clinical Trials

Ongoing phase IV trials are exploring Kanevacil's long-term safety profile in specific patient populations, as well as its efficacy in chronic pain management when combined with other therapies.

Lab Monitoring

Regular monitoring of renal function (serum creatinine, BUN) in long-term therapy or in patients with risk factors.
Liver function tests (LFTs) periodically, especially in patients with pre-existing hepatic impairment.
Complete Blood Count (CBC) to check for anemia, especially with long-term use.

Doctor Notes

Advise patients to report any signs of gastrointestinal bleeding (e.g., black, tarry stools) immediately.
Caution in patients with a history of hypertension or heart failure due to fluid retention risk.
Consider gastroprotective agents for high-risk patients on long-term therapy.

Patient Guidelines

Always take Kaneva with food or milk to reduce stomach upset.
Do not exceed the recommended dose or duration of treatment.
Inform your doctor if you experience any unusual symptoms or side effects.
Avoid concurrent use with other NSAIDs or aspirin without consulting your doctor.

Missed Dose Advice

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Driving Precautions

Kaneva may cause dizziness or drowsiness in some individuals. If you experience these effects, avoid driving or operating machinery.

Lifestyle Advice

Avoid smoking and excessive alcohol consumption, as these can increase the risk of stomach ulcers and bleeding.
Maintain a healthy diet and stay hydrated.