m-min
Generic Name
Magnesium Orotate
Manufacturer
Generic Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
m min 500 mg tablet | ৳ 3.01 | ৳ 30.10 |
Description
Overview of the medicine
Magnesium Orotate is a magnesium salt of orotic acid, used as a mineral supplement to support various bodily functions.
Uses & Indications
Dosage
Adults
Typically 500-1000 mg (as Magnesium Orotate) once or twice daily, or as directed by a healthcare professional.
Elderly
Same as adults, but may need dose adjustment in renal impairment.
Renal_impairment
Dose reduction or avoidance may be necessary due to risk of hypermagnesemia; consult physician.
How to Take
Oral. May be taken with or without food. Taking with food may reduce gastrointestinal upset.
Mechanism of Action
Replenishes magnesium stores; magnesium acts as a co-factor in over 300 enzymatic reactions, crucial for muscle and nerve function, blood glucose control, and blood pressure regulation. Orotate may enhance magnesium absorption.
Pharmacokinetics
Onset
Gradual, effects typically seen over days to weeks of consistent use.
Excretion
Primarily renal (kidneys) for excess magnesium; small amounts via feces.
Half life
Approximately 42 hours for intracellular magnesium.
Absorption
Variable, enhanced by orotate. Occurs primarily in the small intestine.
Metabolism
Magnesium itself is not metabolized; orotic acid is metabolized to pyrimidines.
Side Effects
Contraindications
- Hypersensitivity to magnesium or orotic acid
- Severe renal failure
- Heart block
- Myasthenia gravis
Drug Interactions
Calcium channel blockers
May enhance hypotensive effect.
Diuretics (e.g., furosemide)
Some diuretics can increase magnesium excretion, while potassium-sparing diuretics can increase magnesium levels.
Certain antibiotics (e.g., tetracyclines, quinolones)
Magnesium can decrease absorption of these antibiotics. Take magnesium at least 2 hours before or 4-6 hours after.
Storage
Store in a cool, dry place, away from direct sunlight. Keep out of reach of children.
Overdose
Symptoms include nausea, vomiting, diarrhea, flushing, lethargy, muscle weakness, hypotension, bradycardia, respiratory depression. Severe cases may lead to cardiac arrest. Management involves supportive care, intravenous fluids, and calcium gluconate if severe hypermagnesemia occurs.
Pregnancy & Lactation
Generally considered safe at recommended doses, but always consult a doctor before use during pregnancy or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies, health stores, and online
Approval Status
Approved by national regulatory bodies for OTC use
Patent Status
Off-patent
Clinical Trials
Ongoing research on magnesium orotate's role in cardiovascular health and exercise performance.
Lab Monitoring
- Not routinely required for healthy individuals. May be monitored in patients with renal impairment or specific medical conditions.
Doctor Notes
- Advise patients on potential laxative effect.
- Counsel on drug interactions with antibiotics.
- Emphasize importance of renal function assessment in at-risk patients.
Patient Guidelines
- Take as directed
- Do not exceed recommended dose
- Inform doctor of all medications and supplements
- Store at room temperature
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. Do not double the dose.
Driving Precautions
Generally none. If experiencing dizziness or severe fatigue, avoid driving.
Lifestyle Advice
- Maintain a balanced diet
- Stay hydrated
- Regular exercise can also support muscle health
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
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