Medicine Information

Neo-B

Name: Neo-B
Brand: Neo-B
Rating: 4.5 (117 reviews)

Ointment5 mg per gramTopical AntibioticsATC: D06AX04

Generic Name

Neomycin Sulfate 5 mg Ointment

Manufacturer

Hypothetical Pharma Co.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
neo b 5 mg ointment	৳ 32.60	N/A

Description

Overview of the medicine

Neo-B 5 mg Ointment is a topical antibiotic medication containing Neomycin Sulfate. It is used to treat various bacterial skin infections and prevent infections in minor cuts, scrapes, and burns.

Uses & Indications

Treatment of minor skin infections (e.g., impetigo, folliculitis)

Prevention of infection in minor cuts, scrapes, and burns

Superficial bacterial infections

Dosage

Adults

Apply a thin layer to the affected area 1-3 times daily, or as directed by a physician.

Elderly

No specific dosage adjustment required for elderly patients.

Renal_impairment

Minimal systemic absorption, so dosage adjustment generally not required for topical use. Use with caution on large areas of denuded skin in patients with renal impairment.

How to Take

For external use only. Wash hands before and after application. Clean the affected area thoroughly before applying the ointment.

Mechanism of Action

Neomycin is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and leading to bacterial cell death.

Pharmacokinetics

Onset

Local antimicrobial effect within hours of application.

Excretion

Mainly excreted unchanged in urine after systemic absorption. Unabsorbed drug is excreted in feces.

Half life

Not well-defined for topical application due to minimal systemic absorption; for systemic use, typically 2-3 hours.

Absorption

Minimal systemic absorption through intact skin. Absorption may increase from denuded skin, burns, or ulcerated areas.

Metabolism

Minimal metabolism after topical application.

Side Effects

Contraindications

Hypersensitivity to Neomycin or any other aminoglycoside antibiotics
Viral or fungal skin infections
Tuberculous or syphilitic lesions of the skin

Drug Interactions

Systemic aminoglycosides

Increased risk of ototoxicity and nephrotoxicity if significant systemic absorption occurs with concurrent systemic aminoglycoside use.

Storage

Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.

Overdose

Topical overdose is unlikely to cause systemic toxicity due to poor absorption. Excessive application may lead to local skin irritation. If accidental ingestion occurs, seek medical attention.

Pregnancy & Lactation

Use during pregnancy and lactation only if clearly needed and after consulting a physician, as systemic absorption, though minimal, is possible. Aminoglycosides can potentially cause fetal harm (e.g., ototoxicity) if significant systemic exposure occurs.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5 gram tube10 gram tube15 gram tube

Shelf Life

24-36 months from manufacturing date.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Due to its long-standing use, major recent clinical trials for topical Neomycin as a single agent are rare. Efficacy is well-established through historical clinical data.

Lab Monitoring

No routine lab monitoring is required for topical Neomycin use on intact skin.

Doctor Notes

Counsel patients on proper application technique and hygiene.
Monitor for signs of allergic reaction or superinfection.
Advise against prolonged use to minimize resistance and sensitization risks.

Patient Guidelines

Do not use for more than 7-10 days without consulting a doctor.
Avoid contact with eyes, nose, and mouth.
Discontinue use if irritation or sensitivity develops and consult a physician.

Missed Dose Advice

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply a double dose.