Medicine Information

Eclo

Name: Eclo
Brand: Eclo
Rating: 4.5 (117 reviews)

Cream0.05%Topical CorticosteroidsATC: D07AC16

Generic Name

Eclometasone Dipropionate 0.05% Cream

Manufacturer

Generic Pharma

Country

Global

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
eclo 005 cream	৳ 58.00	N/A

Description

Overview of the medicine

Eclo-005-cream contains Eclometasone Dipropionate, a corticosteroid used to reduce inflammation, itching, and redness in various skin conditions such as eczema and dermatitis.

Uses & Indications

Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses

Eczema (atopic, discoid, stasis)

Psoriasis (except widespread plaque psoriasis)

Contact dermatitis

Neurodermatitis

Dosage

Adults

Apply a thin film to the affected skin areas once or twice daily, or as directed by a physician. Rub in gently and completely.

Elderly

Similar to adult dosage; caution advised for long-term use on large areas.

Renal_impairment

No specific dosage adjustment required for topical application.

How to Take

For external use only. Apply a thin layer to the affected area and gently rub in. Wash hands thoroughly before and after application (unless hands are the treated area). Do not cover the treated area with occlusive dressings unless directed by a doctor.

Mechanism of Action

Eclometasone Dipropionate acts as a glucocorticoid receptor agonist. It suppresses the migration of neutrophils, reduces the production of inflammatory mediators, reverses increased capillary permeability, and exerts anti-inflammatory, antipruritic, and vasoconstrictive actions.

Pharmacokinetics

Onset

Anti-inflammatory effects typically begin within hours to days of initial application.

Excretion

Metabolites are excreted primarily in the urine and feces if systemically absorbed.

Half life

Not well-defined for topical application due to minimal systemic absorption.

Absorption

Systemic absorption of topical corticosteroids can occur, especially through damaged skin or with occlusive dressings. It is generally minimal.

Metabolism

Primarily metabolized in the skin, with any systemically absorbed drug metabolized extensively in the liver.

Side Effects

Contraindications

Hypersensitivity to Eclometasone Dipropionate or any component of the cream
Untreated cutaneous infections (viral, bacterial, fungal)
Acne vulgaris, rosacea
Perioral dermatitis
Pruritus without inflammation

Drug Interactions

Systemic corticosteroids

Concurrent use may increase the risk of systemic corticosteroid side effects, although generally minimal with topical use.

Storage

Store below 30°C. Protect from light and moisture. Keep out of reach of children.

Overdose

Acute overdose is unlikely. Chronic excessive use or misuse may lead to systemic corticosteroid effects, including adrenal suppression. Treatment is symptomatic and supportive; gradual withdrawal of the steroid may be necessary.

Pregnancy & Lactation

Use in pregnancy only if the potential benefit justifies the potential risk to the fetus. Avoid large areas or prolonged use. Exercise caution when administering to a nursing mother; consult your doctor before use.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

5g tube10g tube15g tube30g tube

Shelf Life

Typically 24 to 36 months from the manufacturing date.

Availability

Pharmacies, hospitals

Approval Status

Approved by health authorities

Patent Status

Generic available

Clinical Trials

Eclometasone Dipropionate has undergone various clinical trials demonstrating its efficacy and safety in treating corticosteroid-responsive dermatoses. Specific trials for generic Eclo-005-cream would focus on bioequivalence.

Lab Monitoring

For extensive or prolonged use, monitoring of HPA axis suppression (e.g., ACTH stimulation test) may be considered, especially in children.

Doctor Notes

Advise patients on appropriate application technique and the importance of not exceeding the prescribed duration.
Caution against use on the face, intertriginous areas, or for prolonged periods, especially in children and infants.
Educate patients about potential signs of skin atrophy or systemic absorption and when to seek medical advice.

Patient Guidelines

Use only as directed by your doctor and for the prescribed duration.
Avoid contact with eyes, nose, mouth, and other mucous membranes.
Do not use on the face, groin, or axillae unless specifically advised by your doctor.
Do not bandage or cover the treated area with occlusive dressings unless instructed by a physician.
Inform your doctor if your condition worsens or does not improve after 2 weeks of treatment.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply extra cream to make up for a missed dose.

Driving Precautions

Topical Eclometasone Dipropionate is not expected to affect the ability to drive or operate machinery.

Lifestyle Advice

Keep the affected skin moisturized. Avoid known irritants or allergens that may trigger your skin condition.
Wear loose-fitting clothing over treated areas.