Medicine Information

Gensulin-R

Name: Gensulin-R
Brand: Gensulin-R
Rating: 4.5 (117 reviews)

Injection100 IU/mlAntidiabeticATC: A10AB01

Generic Name

Insulin Human (rDNA origin)

Manufacturer

Bioton S.A.

Country

Poland

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
gensulin r 100 iu injection	৳ 415.00	N/A

Description

Overview of the medicine

Gensulin-R is a rapid-acting human insulin used to control high blood sugar levels in people with diabetes mellitus.

Uses & Indications

Diabetes mellitus (Type 1 and Type 2)

Diabetic ketoacidosis (DKA)

Hyperkalemia

Dosage

Adults

Individualized based on patient's metabolic needs, blood glucose monitoring, and glycemic control target. Typically administered subcutaneously 30 minutes before meals.

Elderly

Similar to adults, but careful monitoring may be required due to potential renal impairment.

Renal_impairment

Dosage adjustments may be necessary due to reduced insulin clearance.

How to Take

Subcutaneous injection (thigh, upper arm, abdomen, buttock) 30 minutes before a meal. Can be given intravenously by medical professionals in emergencies.

Mechanism of Action

Lowers blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production.

Pharmacokinetics

Onset

30-60 minutes

Excretion

Mainly via the kidneys.

Half life

Approximately 5-10 minutes (plasma), but effective half-life is longer due to absorption kinetics.

Absorption

Rapidly absorbed after subcutaneous injection.

Metabolism

Primarily degraded by insulin-degrading enzyme in the liver and kidney.

Side Effects

Contraindications

Hypoglycemia
Hypersensitivity to insulin or excipients

Drug Interactions

Alcohol

Can enhance the blood glucose-lowering effect of insulin.

Beta-blockers

Can mask symptoms of hypoglycemia.

Corticosteroids

May increase blood glucose, requiring higher insulin doses.

Oral contraceptives

May increase insulin requirements.

Storage

Store unopened in a refrigerator (2-8°C). Do not freeze. Protect from light. Once opened, store at room temperature (below 30°C) for up to 28 days.

Overdose

Leads to hypoglycemia (low blood sugar). Management involves oral glucose (mild cases) or intravenous glucose/glucagon (severe cases).

Pregnancy & Lactation

Safe for use, but dosage adjustments may be required throughout pregnancy and lactation. Close monitoring is essential.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

10 ml vial (1000 IU)3 ml cartridge (300 IU)

Shelf Life

Typically 2-3 years unopened when stored in refrigerator; 28 days after first use when stored at room temperature.

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Extensively studied in clinical trials for efficacy and safety in diabetes management, demonstrating its role as a cornerstone therapy.

Lab Monitoring

Blood glucose levels (fasting, post-prandial)
HbA1c
Electrolytes (if hyperkalemia)

Doctor Notes

Educate patients on proper injection technique, site rotation, and hypoglycemia management.
Regular monitoring of blood glucose and HbA1c is crucial to optimize therapy and prevent complications.
Adjust dose based on patient's lifestyle, diet, and exercise regimen.

Patient Guidelines

Always check insulin type and strength before injection.
Rotate injection sites to prevent lipodystrophy.
Carry a source of fast-acting glucose for hypoglycemia.

Missed Dose Advice

If a meal is delayed or skipped, the dose of Gensulin-R should be adjusted or omitted. Consult your doctor.

Driving Precautions

Caution is advised, especially at the start of treatment or during dose changes, due to the risk of hypoglycemia affecting concentration.

Lifestyle Advice

Maintain a healthy diet and regular exercise.
Monitor blood glucose regularly.

Alternative Medicines in Bangladesh

Similar medicines available in the market

Insuget-R (Incepta)Insugen-R (ACI)Diabet-R (Square)

Global Brand Names

International brand names for this medicine

Incepta Pharmaceuticals Ltd.

Tablet60 mg, 90 mg, 120 mg

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