Hemoral
Generic Name
Diosmin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| hemoral 450 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Diosmin is a naturally occurring flavonoid glycoside used as a phlebotonic and vascular protecting agent. It is primarily used in the treatment of venous insufficiency and hemorrhoids.
Uses & Indications
Dosage
Adults
For chronic venous insufficiency: 1 tablet daily. For acute hemorrhoidal attacks: 3 tablets twice daily for the first 4 days, then 2 tablets twice daily for 3 days. For chronic hemorrhoids: 1 tablet daily.
Elderly
No specific dose adjustment required.
Renal_impairment
No specific dose adjustment required, but caution is advised.
How to Take
Oral. Taken with meals.
Mechanism of Action
Diosmin prolongs the vasoconstrictor effect of noradrenaline on the venous wall, increasing venous tone. It also reduces capillary hyperpermeability and improves lymphatic drainage.
Pharmacokinetics
Onset
Effects observed within hours for acute conditions; long-term benefits for chronic conditions.
Excretion
Excreted mainly via feces (80%) and urine (14%).
Half life
Approximately 11 hours.
Absorption
Rapidly absorbed after oral administration, extensively metabolized.
Metabolism
Extensively metabolized to phenolic acids, mainly by intestinal flora.
Side Effects
Contraindications
- Hypersensitivity to Diosmin or any component of the formulation.
- Lactating mothers.
Drug Interactions
No significant interactions
No significant drug interactions have been reported with Diosmin. However, caution is advised with drugs that affect coagulation due to potential vascular effects.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Limited data on overdose. Symptoms may include gastrointestinal disturbances. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy: Use only if clearly needed after consulting a doctor. Lactation: Contraindicated during lactation as data on excretion into breast milk is insufficient.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generic available
Clinical Trials
Numerous clinical trials have supported the efficacy of Diosmin in treating venous insufficiency and hemorrhoids.
Lab Monitoring
- No specific lab monitoring required.
Doctor Notes
- Advise patients on lifestyle modifications along with medication for optimal outcomes in CVI and hemorrhoids.
- Counsel on compliance, especially during acute hemorrhoidal episodes, for proper duration.
Patient Guidelines
- Follow your doctor's instructions carefully.
- Take the tablet with meals.
- Do not stop taking the medicine abruptly without consulting your doctor.
Missed Dose Advice
Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
No known effects on the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a healthy lifestyle, including regular exercise and a balanced diet.
- Avoid prolonged standing or sitting.
- Elevate legs when resting to improve circulation.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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