Medicine Information

Kemet

Name: Kemet
Brand: Kemet
Rating: 4.5 (117 reviews)

Suspension200 mgAnti-bacterial (3rd generation Cephalosporins)ATC: J01DD14

Generic Name

Ceftibuten 200 mg Suspension

Manufacturer

Eskayef Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
kemet 200 mg suspension	৳ 29.80	N/A

Description

Overview of the medicine

Ceftibuten is a third-generation cephalosporin antibiotic used to treat various bacterial infections, primarily in pediatric patients. It is administered orally as a suspension.

Uses & Indications

Acute bacterial otitis media

Acute exacerbation of chronic bronchitis

Pharyngitis/Tonsillitis

Community-acquired pneumonia

Urinary tract infections

Dosage

Adults

Not typically used in adults; if used, dosage might be 400 mg once daily.

Elderly

Not specifically studied; dose adjustment may be needed based on renal function.

Renal_impairment

Dose reduction required for creatinine clearance < 50 mL/min.

How to Take

Administer orally. Can be taken with or without food. Ensure proper shaking of the suspension before use.

Mechanism of Action

Ceftibuten inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis and death.

Pharmacokinetics

Onset

Typically within hours.

Excretion

Primarily via urine.

Half life

Approximately 2 to 4 hours.

Absorption

Rapidly absorbed from the gastrointestinal tract; food may delay absorption but not total amount.

Metabolism

Primarily excreted unchanged; minimal hepatic metabolism.

Side Effects

Contraindications

Hypersensitivity to ceftibuten or other cephalosporins
History of severe hypersensitivity reaction to any beta-lactam antibiotic

Drug Interactions

Probenecid

May increase ceftibuten plasma levels by reducing renal excretion.

Oral anticoagulants (e.g., warfarin)

May enhance anticoagulant effect, requiring monitoring of INR.

Storage

Store below 30°C, protected from light and moisture. Do not freeze.

Overdose

Symptomatic and supportive treatment. Hemodialysis may be useful in overdose.

Pregnancy & Lactation

Use during pregnancy only if clearly needed. Excreted in human milk in small amounts; use with caution during lactation.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

30 ml suspension

Shelf Life

24 months (unopened); 7-14 days after reconstitution

Availability

Pharmacies, Hospitals

Approval Status

Approved

Patent Status

Expired

Clinical Trials

Extensive clinical trials have demonstrated its efficacy and safety in treating pediatric bacterial infections.

Lab Monitoring

Renal function (for prolonged therapy or renal impairment)
Liver function tests (if abnormalities observed)

Doctor Notes

Prescribe appropriate duration to prevent resistance.
Advise parents on proper measurement and administration.
Monitor for signs of C. difficile-associated diarrhea.

Patient Guidelines

Complete the full course of treatment as prescribed, even if symptoms improve.
Shake the suspension well before each use.
Store at room temperature, away from moisture and heat.

Missed Dose Advice

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.