Medicine Information

Fluvate

Name: Fluvate
Brand: Fluvate
Rating: 4.5 (117 reviews)

Ointment0.05% w/wTopical CorticosteroidATC: D07AC04

Generic Name

Fluocinolone Acetonide Ointment

Manufacturer

ABC Pharma

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
fluvate 0005 ointment	৳ 50.35	N/A

Description

Overview of the medicine

Fluvate-0005-ointment contains Fluocinolone Acetonide, a potent corticosteroid used to reduce inflammation, itching, and redness in various skin conditions such as eczema, psoriasis, and dermatitis.

Uses & Indications

Eczema

Psoriasis

Dermatitis (e.g., contact dermatitis, atopic dermatitis)

Other inflammatory and pruritic skin conditions

Dosage

Adults

Apply a thin layer to the affected skin area 2-3 times daily, or as directed by the physician. Do not use for more than 2 weeks without medical advice.

Elderly

Similar to adult dosage. Use with caution, especially for prolonged periods, due to increased skin fragility in some elderly patients.

Renal_impairment

No specific dosage adjustment is generally required for topical use in renal impairment.

How to Take

For external use only. Apply a small amount of ointment to the affected area and rub it gently until it disappears. Wash hands before and after application. Avoid contact with eyes, mouth, and other mucous membranes.

Mechanism of Action

Fluocinolone Acetonide works by inhibiting the release of chemicals that cause inflammation in the body. It has anti-inflammatory, antipruritic (anti-itching), and vasoconstrictive (narrowing of blood vessels) properties.

Pharmacokinetics

Onset

Anti-inflammatory effects can be observed within hours to a day after application.

Excretion

Excreted mainly by the kidneys.

Half life

The systemic half-life of absorbed Fluocinolone Acetonide is not precisely defined for topical application; however, it is metabolized in the liver.

Absorption

Absorption through the skin is variable and depends on the integrity of the epidermal barrier, application site, and use of occlusive dressings. Systemic absorption can occur.

Metabolism

Primarily metabolized in the liver to inactive metabolites.

Side Effects

Contraindications

Hypersensitivity to Fluocinolone Acetonide or any component of the ointment
Primary cutaneous viral infections (e.g., herpes simplex, varicella)
Primary bacterial or fungal skin infections (unless concurrent appropriate anti-infective therapy is used)
Acne vulgaris, rosacea, perioral dermatitis
Ulcerative conditions, perianal and genital pruritus

Drug Interactions

No significant systemic drug interactions

Systemic absorption of topical Fluocinolone Acetonide is generally low, so significant drug interactions are unlikely. However, avoid concurrent use of other potent topical corticosteroids on the same area.

Storage

Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.

Overdose

Acute overdose is unlikely with topical use. However, prolonged or excessive use of corticosteroids, especially over large surface areas or under occlusive dressings, can lead to systemic effects such as Cushing's syndrome, hyperglycemia, and adrenal suppression. Symptomatic treatment is recommended.

Pregnancy & Lactation

Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Topical corticosteroids should not be used extensively or for prolonged periods during pregnancy. Exercise caution when administering to a nursing mother; avoid applying to breast area.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

15 gm tube30 gm tube

Shelf Life

Typically 24 to 36 months from the manufacturing date when stored correctly.

Availability

Available in pharmacies and hospitals

Approval Status

Approved by regulatory authorities

Patent Status

Off-patent

WHO Essential Medicine

Yes

Clinical Trials

Extensive clinical trials have demonstrated the efficacy and safety of Fluocinolone Acetonide in treating various inflammatory dermatoses. Studies confirm its potent anti-inflammatory and antipruritic effects.

Lab Monitoring

Routine lab monitoring is not typically required for topical Fluocinolone Acetonide. However, if used extensively or for prolonged periods, especially in children, monitoring for adrenal axis suppression may be considered.

Doctor Notes

Emphasize proper application technique and limit treatment duration, especially on sensitive areas like the face.
Educate patients on potential side effects and when to seek medical attention.
Consider lower potency corticosteroids for maintenance or less severe conditions.

Patient Guidelines

Use only as directed by your doctor. Do not apply to the face, groin, or armpits unless specifically advised by your doctor.
Avoid using on broken or infected skin without medical advice.
Do not cover the treated area with bandages or other occlusive dressings unless instructed by your doctor.
Wash your hands before and after applying the ointment.
Do not use for longer than the prescribed duration.

Missed Dose Advice

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.